Escola Paulista de Medicina
Programa de Pós-Graduação em Nefrologia

Alexandre De Castro Keller

Contato | Currículo Lattes

Orientações em Andamento:

Data de Matrícula Aluno Programa de Pós-Graduação Nível
01/03/2017 MICHELANGELO BAUWELZ GONZATTI Microbiologia e Imunologia (33009015003P3) MESTRADO
01/03/2015 ALESSANDRA LIMA DA SILVA MARTINS Medicina (Nefrologia) (33009015016P8) MESTRADO

Orientações Concluídas:

Data de Titulação Aluno Programa de Pós-Graduação Nível
31/10/2016 JOES NOGUEIRA NETO Microbiologia e Imunologia (33009015003P3) DOUTORADO
31/12/2015 ANA PAULA FERNANDES DA SILVA MONTEIRO Medicina (Nefrologia) (33009015016P8) DOUTORADO
30/09/2015 VANESSA OLIVEIRA DOS REIS Microbiologia e Imunologia (33009015003P3) DOUTORADO
30/06/2015 DAVID ANIBAL GARRIDO ANDRADE Microbiologia e Imunologia (33009015003P3) DOUTORADO
30/09/2014 NATHÁLIA AMATO KHALED Microbiologia e Imunologia (33009015003P3) MESTRADO
25/07/2012 JANICE DA COSTA SILVA Medicina (Nefrologia) (33009015016P8) MESTRADO
27/07/2011 VANESSA OLIVEIRA DOS REIS Medicina (Nefrologia) (33009015016P8) MESTRADO

Artigos Completos Publicados em Periódicos Científicos:

  1. PEREIRA, R. L. ; FELIZARDO, R. J. F. ; CENEDEZE, M. A. ; HIYANE, M. I. ; BASSI, E. J. ; AMANO, M. T. ; ORIGASSA, C. S. T. ; SILVA, R. C. ; AGUIAR, C. F. ; CARNEIRO, S. M. ; PESQUERO, J. B. ; ARAUJO, R. C. ; KELLER, A. D. C. ; MONTEIRO, R. ; MOURA, I. C. ; Pacheco-Silva, A. ; CAMARA, N. O. S.. The balance of kinin receptors in the progression of experimental focal and segmental glomerulosclerosis. DIS MODEL MECH. v. DIS MODEL MECH, p. 1, 2014. http://dx.doi.org/10.1242/dmm.014548
  2. VIVANCO, B. C. ; VIANA, J. D. ; HURTADO, E. C. P. ; KONNO, F. T. C. ; GUERESCHI, M. ; Xander, P. ; Lopes, J.D. ; KELLER, A. C.. B-1 cells promote immunosurveillance against murine melanoma in host absence of CCR5: New perspective in autologous vaccination therapy. Immunobiology (Jena. 1979). v. Immunobiology (Jena. 1979), p. 1, 2014. http://dx.doi.org/10.1016/j.imbio.2014.07.013
  3. GUERESCHI, M. ; ARAUJO, L. P. ; MARICATO, J. T. ; TAKENAKA, M. C. ; NASCIMENTO, V. M. ; VIVANCO, B. C. ; REIS, V. O. ; KELLER, A. C. ; BRUM, P. C. ; BASSO, A. S.. Beta2 adrenergic receptor signaling in CD4+ Foxp3+ regulatory T cells enhances their suppressive function in a PKA-dependent manner. European Journal of Immunology. v. European Journal of Immunology, p. 1001, 2013. http://dx.doi.org/10.1002/eji.201243005
  4. BERNARDINO, SIMONE ; PINA, ADRIANA ; FELONATO, MAÍRA ; COSTA, TÂNIA A. ; FRANK DE ARAÚJO, ELISEU ; FERIOTTI, CLÁUDIA ; BAZAN, SILVIA BOSCHI ; Keller, Alexandre C. ; LEITE, KATIA R. M. ; CALICH, VERA L. G.. TNF-α and CD8+ T Cells Mediate the Beneficial Effects of Nitric Oxide Synthase-2 Deficiency in Pulmonary Paracoccidioidomycosis. PLoS Neglected Tropical Diseases (Online). v. PLoS Neglected Tropical Diseases (Online), p. e2325, 2013. http://dx.doi.org/10.1371/journal.pntd.0002325
  5. Faustino, Lucas ; Mucida, Daniel ; Keller, Alexandre Castro ; Demengeot, Jocelyne ; Bortoluci, Karina ; Sardinha, Luiz Roberto ; Carla Takenaka, Maisa ; Basso, Alexandre Salgado ; Faria, Ana Maria Caetano ; Russo, Momtchilo. Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production. Clinical & Developmental Immunology (Print). v. Clinical & Developmental Immunology (Print), p. 1-13, 2012. http://dx.doi.org/10.1155/2012/721817
  6. Pereira, Rafael L. ; Reis, Vanessa O. ; Semedo, Patricia ; Buscariollo, Bruna N. ; Donizetti-Oliveira, Cassiano ; Cenedeze, Marcos A. ; Soares, Maria Fernanda ; Pacheco-Silva, Alvaro ; Savage, Paul B. ; Câmara, Niels O. S. ; Keller, Alexandre C.. Invariant Natural Killer T Cell Agonist Modulates Experimental Focal and Segmental Glomerulosclerosis. Plos One. v. Plos One, p. e32454, 2012. http://dx.doi.org/10.1371/journal.pone.0032454
  7. Elias, Rosa Maria ; Correa-Costa, Matheus ; Barreto, Claudiene Rodrigues ; Silva, Reinaldo Correia ; Hayashida, Caroline Y. ; Castoldi, Ângela ; Gonçalves, Giselle Martins ; Braga, Tarcio Teodoro ; Barboza, Renato ; Rios, Francisco José ; Keller, Alexandre Castro ; Cenedeze, Marcos Antonio ; Hyane, Meire Ioshie ; D' ; Figueiredo-Neto, Antônio Martins ; Reis, Marlene Antônia ; Marinho, Cláudio Romero Farias ; Pacheco-Silva, Alvaro ; Câmara, Niels Olsen Saraiva ; Costa, Fabio T. M.. Oxidative Stress and Modification of Renal Vascular Permeability Are Associated with Acute Kidney Injury during P. berghei ANKA Infection. Plos One. v. Plos One, p. e44004, 2012. http://dx.doi.org/10.1371/journal.pone.0044004
  8. MESNARD, L. ; RAFAT, C. ; VANDERMEERSCH, S. ; Hertig, A. ; Cathelin, D. ; Xu-Dubois, Y.-C. ; Jouanneau, C. ; Castro Keller, A. ; Ribeil, J.-A. ; LEITE-DE-MORAES, M. C. ; RONDEAU, E.. Vitronectin dictates intraglomerular fibrinolysis in immune-mediated glomerulonephritis. The FASEB Journal. v. The FASEB Journal, p. 000-000, 2011. http://dx.doi.org/10.1096/fj.11-180752
  9. Reis, Vanessa Oliveira ; Silva, Janice Costa ; Souza, Gabriela Trindade ; Semedo, Patricia ; Buscariollo, Bruna ; Pereira, Rafael Luiz ; Cenedeze, Marcos Antonio ; Pacheco-Silva, Alvaro ; Longo-Maugéri, Ieda M. ; Câmara, Niels Olsen Saraiva ; Keller, Alexandre Castro. The polysaccharide fraction of Propionibacterium acnes modulates the development of experimental focal segmental glomerulosclerosis. Immunobiology (Jena. 1979). v. Immunobiology (Jena. 1979), p. 1-11, 2011. http://dx.doi.org/10.1016/j.imbio.2011.12.003
  10. Pereira, Rafael L ; Buscariollo, Bruna N ; Corrêa-Costa, Matheus ; Semedo, Patricia ; Oliveira, Cassiano D ; Reis, Vanessa O ; Maquigussa, Edgar ; Araújo, Ronaldo C ; Braga, Tárcio T ; Soares, Maria F ; Moura, Ivan C ; Malheiros, Denise M A C ; Filho, Alvaro Pacheco-Silva ; Keller, Alexandre C ; Câmara, Niels O S. Bradykinin receptor 1 activation exacerbates experimental focal and segmental glomerulosclerosis. Kidney International. v. Kidney International, p. 111, 2011. http://dx.doi.org/10.1038/ki.2011.14
  11. Correa-Costa, Matheus ; Semedo, Patricia ; Monteiro, Ana Paula F. S. ; Silva, Reinaldo C. ; Pereira, Rafael L. ; Gonçalves, Giselle M. ; Marques, Georgia Daniela Marcusso ; Cenedeze, Marcos A. ; Faleiros, Ana C. G. ; Keller, Alexandre C. ; Shimizu, Maria H. M. ; Seguro, Antônio C. ; Reis, Marlene A. ; Pacheco-Silva, Alvaro ; Câmara, Niels O. S.. Induction of Heme Oxygenase-1 Can Halt and Even Reverse Renal Tubule-Interstitial Fibrosis. Plos One. v. Plos One, p. e14298, 2010. http://dx.doi.org/10.1371/journal.pone.0014298
  12. Keller, A. D.C.; MESNARD, L. ; Michel, M.-L. ; VANDERMEERSCH, S. ; RAFAT, C. ; LETAVERNIER, E. ; TILLET, Y. ; RONDEAU, E. ; LEITE-DE-MORAES, M. C.. Invariant Natural Killer T Cells and TGF-  Attenuate Anti-GBM Glomerulonephritis. Journal of the American Society of Nephrology. v. Journal of the American Society of Nephrology, p. 1282-1292, 2009. http://dx.doi.org/10.1681/ASN.2008040433
  13. Christ, A. P. ; RODRIGUEZ, D. ; Bortolatto, J. ; BORDUCCHI, E. ; Keller, A. ; Mucida, D. ; Silva, J. S. ; Leite, L. C.C. ; RUSSO, M.. Enhancement of Th1 Lung Immunity Induced by Recombinant Mycobacterium bovis BCG Attenuates Airway Allergic Disease. American Journal of Respiratory Cell and Molecular Biology. v. American Journal of Respiratory Cell and Molecular Biology, p. 1, 2009. http://dx.doi.org/10.1165/rcmb.2009-0040OC
  14. ROGERIO, A ; FONTANARI, C ; BORDUCCHI, E ; KELLER, A. C. ; RUSSO, M ; SOARES, E ; ALBUQUERQUE, D ; FACCIOLI, L. Anti-inflammatory effects of Lafoensia pacari and ellagic acid in a murine model of asthma. European Journal of Pharmacology. v. European Journal of Pharmacology, p. 262-270, 2008. http://dx.doi.org/10.1016/j.ejphar.2007.10.034
  15. LETAVERNIER, E. ; PEREZ, J. ; BELLOQ, A. ; MESNARD, L. ; de Castro Keller, A. ; HAYMANN, J. P. ; BAUD, L.. Targeting the Calpain/Calpastatin System as a New Strategy to Prevent Cardiovascular Remodeling in Angiotensin II-Induced Hypertension. Circulation Research. v. Circulation Research, p. 720-728, 2008. http://dx.doi.org/10.1161/CIRCRESAHA.107.160077
  16. MENDEZ-DA-CRUZ, D. A. ; SMANIOTTO, S. ; KELLER, A. C. ; Dardenne, M. ; SAVINO, W.. Multivectorial Abnormal Cell Migration in the NOD Mouse Thymus.. Journal of Immunology (Baltimore). v. Journal of Immunology (Baltimore), p. 4639-4647, 2008.
  17. Bortolatto, J. ; Borducchi, É. ; RODRIGUEZ, D. ; KELLER, A. C. ; Faquim-Mauro, E. ; Bortoluci, K. R. ; Mucida, D. ; GOMES, E. ; Christ, A. ; SCHNYDER-CANDRIAN, S. ; SCHNYDER, B. ; RYFFEL, B. ; RUSSO, M.. Toll-like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin-specific allergic airway disease: role of MyD88 adaptor molecule and interleukin-12/interferon-? axis. Clinical and Experimental Allergy. v. Clinical and Experimental Allergy, p. 1668-1679, 2008. http://dx.doi.org/10.1111/j.1365-2222.2008.03036.x
  18. Michel, M.-L. ; Mendes-da-Cruz, D. ; KELLER, A. C. ; Lochner, M. ; SCHNEIDER, E. ; DY, M. ; Eberl, G. ; LEITE-DE-MORAES, M. C.. Critical role of ROR- t in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation. PNAS. Proceedings of the National Academy of Sciences of the United States of America. v. PNAS. Proceedings of the National Academy of Sciences of the United States of America, p. 19845-19850, 2008. http://dx.doi.org/10.1073/pnas.0806472105
  19. Mallevaey, T. ; Fontaine, J. ; Breuilh, L. ; Paget, C. ; Castro-Keller, A. ; Vendeville, C. ; Capron, M. ; Leite-de-Moraes, M. ; Trottein, F. ; Faveeuw, C. ; Castro-Keller A.. Invariant and Noninvariant Natural Killer T Cells Exert Opposite Regulatory Functions on the Immune Response during Murine Schistosomiasis. Infection and Immunity. v. Infection and Immunity, p. 2171-2180, 2007. http://dx.doi.org/10.1128/IAI.01178-06
  20. Michel, M.-L. ; KELLER, A. C. ; Paget, C. ; Fujio, M. ; Trottein, F. ; Savage, P. B. ; Wong, C.-H. ; SCHNEIDER, E. ; DY, M. ; LEITE-DE-MORAES, M. C.. Identification of an IL-17-producing NK1.1neg iNKT cell population involved in airway neutrophilia. Journal of Experimental Medicine. v. Journal of Experimental Medicine, p. 995-1001, 2007. http://dx.doi.org/10.1084/jem.20061551
  21. KELLER, A. C.; MUCIDA, D ; GOMES, E ; FAQUIMMAURO, E ; FARIA, A ; RODRIGUEZ, D ; RUSSO, M. Hierarchical suppression of asthma-like responses by mucosal tolerance. Journal of Allergy and Clinical Immunology. v. Journal of Allergy and Clinical Immunology (In press) , p. 283-290, 2006. http://dx.doi.org/10.1016/j.jaci.2005.10.019
  22. Keller, Alexandre Castro; Rodriguez, Dunia ; Russo, Momtchilo. Nitric oxide paradox in asthma. Memórias do Instituto Oswaldo Cruz (Impresso). v. Memórias do Instituto Oswaldo Cruz (Impresso), p. 19-23, 2005. http://dx.doi.org/10.1590/S0074-02762005000900005
  23. PINA, A. ; VALENTE-FERREIRA, R. C. ; MOLINARI-MADLUM, E. E. W. ; VAZ, C. A. C. ; KELLER, A. C. ; CALICH, V. L. G.. Absence of Interleukin-4 Determines Less Severe Pulmonary Paracoccidioidomycosis Associated with Impaired Th2 Response. Infection and Immunity (Print). v. Infection and Immunity (Print) (April) , p. 2369-2378, 2004. http://dx.doi.org/10.1128/IAI.72.4.2369-2378.2004
  24. ARRUDA, C. ; VALENTE-FERREIRA, R. C. ; PINA, A. ; KASHINO, S. S. ; FAZIOLI, R. A. ; VAZ, C. A. C. ; FRANCO, M. F. ; KELLER, A. C. ; CALICH, V. L. G.. Dual Role of Interleukin-4 (IL-4) in pulmonary Paracoccidioidomycosis: Endogenous IL-4 Can Induce Protection or Exacerbation of Disease Depending on the Host Genetic Pattern. Infection and Immunity. v. Infection and Immunity (July) , p. 001-009, 2004.
  25. MUCIDA, DANIEL SOUSA ; MENEZES, JUSCILENE SILVA ; RODRÃ GUEZ, DUNIA ; Keller, Alexandre Castro ; GOMES, ELIANE ; RUSSO, MOMCHILO ; Faria, Ana Maria Caetano. Decreased Nasal Tolerance to Allergic Asthma in Mice Fed an Amino Acid-Based Protein-Free Diet. Annals of the New York Academy of Sciences. v. Annals of the New York Academy of Sciences, p. 361-365, 2004. http://dx.doi.org/10.1196/annals.1309.042
  26. LISBONNE, M. ; DIEM, S. ; KELLER, A. C. ; LEFORT, J. ; ARAUJO, L. M. ; HACHEM, P. ; RUSSO, M. ; VARGAFTIG, B. B. ; HERBELIN, A. ; LEITE-DE-MORAES, M. C.. Cutting Edge: Invariant Valpha 14 NKT Cells Are Required for Allergen-Induced Airway Inflammation and Hyperreactivity in an Experimental Asthma Model. Journal of Immunology (Baltimore). v. Journal of Immunology (Baltimore), p. 1637-1641, 2003.
  27. RODRIGUEZ, D. ; KELLER, A. C. ; FAQUIM-MAURO, E. L. ; MACEDO, M. S. ; CUNHA, F. Q. ; LEFORT, J. ; VARGAFTIG, B. B. ; RUSSO, M.. Bacterial Lypopolissacharide Signalling Through Toll-Like Receptor 4 Suppresses Asthma-like Responses Via Nitric Oxide Synthase 2 Activity. The Journal of Immunology (1950). v. The Journal of Immunology (1950), p. 1001-1008, 2003.
  28. MUCIDA, D. S. ; KELLER, A. C. ; FERNVIK, E. C. ; RUSSO, M.. Unconventional Strategies for the Suppression of Allergic Asthma. Current Drug Targets. Inflammation & Allergy. v. Current Drug Targets. Inflammation & Allergy, p. 187-195, 2003.
  29. RUSSO, M. ; NAHORI, M. ; LEFORT, J. ; GOMES, E. ; KELLER, A. C. ; RODRIGUEZ, D. ; ADRIOUCH, S. ; GALLOIS, V. ; FARIA, A. M. C. ; VARGAFTIG, B. B.. Suppression of Asthma-like Responses in Different Mouse Strains by Oral Tolerance. American Journal of Respiratory Cell and Molecular Biology. v. American Journal of Respiratory Cell and Molecular Biology, p. 518-526, 2001.
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